Aripiprazole 및 Aripiprazole Monthly(Abilify Maintena) 대체 병합 투여로 증상 악화를 보인 만성 조현병 환자

• 영문명: Worsening of Psychotic Symptoms in Patients with Chronic Schizophrenia after Switching to or Combining Aripiprazole and Aripiprazole Monthly (Abilify Maintena)
• 발행기관: 대한신경정신의학회
• 저자명: 박명현(MyeongHyun Michelle Park) 김수룡(Su Ryong Kim) 함웅(Woong Hahm) 백인호(In Ho Paik)
• 간행물 정보: 『신경정신의학』제59권 제2호, 166~169쪽, 전체 4쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2020.05.31

영문 초록

Objectives Aripiprazole is an antipsychotic that functions as a partial agonist in hypodopaminergic states and a dopamine antagonist in hyperdopaminergic states. Methods This paper reports a series of five clinical cases of worsening psychotic symptoms in schizophrenic patients related to the initiation of aripiprazole, oral and injection, as combination therapy. Results In all five cases, the switching of aripiprazole improved the psychotic symptoms. Conclusion Even with the suggestive relationship between aripiprazole therapy and the worsening of psychotic symptoms, further research is needed.

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키워드

Schizophrenia Aripiprazole Combination therapy