급성 두드러기를 주소로 내원한 소아의 혈청 총 IgE 수치와 알레르겐 특이항체 검사에 대한 연구

• 영문명: Study of Total IgE Level and Allergen Specific IgE in Children with Acute Urticaria
• 발행기관: 조선대학교 의학연구원
• 저자명: 조소여(So Yeo Cho) 김은영(Eun Young Kim) 노영일(Young Il Rho) 문경래(Kyung Rye Moon) 박영봉(Yeong Bong Park) 양은석(Eu
• 간행물 정보: 『The Medical Journal of Chosun University』제39권 제4호, 237~243쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2014.12.31

영문 초록

Increased total IgE and eosinophil count levels are thought to provoke the occurrence of urticaria. The purpose of this study is to measure serum total IgE levels, specific IgE sensitization rates, and blood eosinophil count and to investigate the relationship between those factors. Among children who visited the Department of Pediatrics at Chosun University Hospital from January 2011 to December 2013, we retrospectively analyzed 63 patients with acute urticaria. Positive rates of the total serum IgE level, specific IgE, and blood eosinophil count were analyzed in patients with acute urticaria. A total of 63 patients were included in the study and the rate of males to females was 1: 0.8. Mean age of patients was 6.41±4.97 years (range 0-17 years). Among the subjects, 42.9% of patients showed an elevated serum total IgE and 63.5% of patients showed at least more than one allergen-specific IgE by MAST (multiple allergosorbent test). The mean number of allergens detected in positive patients was 2.42±2.56/patient. The serum total IgE and allergen specific IgE showed significant positive correlation (OR = 0.290, p=0.02). This study is meaningful as it revealed a positive correlation between serum total IgE and allergen specific IgE in urticaria patients.

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키워드

Allergen-specific IgE Total IgE Blood eosinophil MAST (multiple allergosorbent test) Urticaria