조현병 재발방지를 위한 약물치료 전략

• 영문명: Pharmacotherapeutic Strategies to Prevent Relapse in Schizophrenia
• 발행기관: 대한신경정신의학회
• 저자명: 김지현(Jihyun Kim) 박염홍(Yanhong Piao) 신광범(Quangfan Shen) 정영철(Young-Chul Chung)
• 간행물 정보: 『신경정신의학』제57권 제3호, 225~229쪽, 전체 5쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2018.08.31

영문 초록

Successful treatment is very high in patients with first episode schizophrenia (FES). On the other hand, the problem is a frequent relapse often caused by non-compliance. The non-compliance rate in patients with FES is 40–60% within 1 year. The causes of non-compliance are diverse, such as poor insight, drug side effects, attitude of caregiver, social stigma, etc. Clinicians should be able to provide appropriate psychosocial intervention and long acting injectable antipsychotics (LAI) to overcome non-compliance. Recently, there is solid and accumulating evidence demonstrating superiority of LAI over oral medication in terms of reducing relapse or rehospitalization. In particular, a substantial portion (approximately 30–50%) of patients and caregivers prefer LAI to oral medication. Shared decision-making is the process that clinicians and patients/caregiver should go through in order to obtain the full benefits from LAI.

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키워드

Compliance Long acting injectable drugs Schizophrenia Shared decision making