개구리 심방(心房)의 Adrenotropic Receptor

• 영문명: Adrenotropic Receptor in the Frog Atria
• 발행기관: 대한약리학회
• 저자명: 조순임(Cho, Soon-Im)
• 간행물 정보: 『대한약리학잡지』제5권 제1호, 35~38쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1969.06.30

영문 초록

1.On isolated atrial preparation of frog, effects of sympathomimetic amines were investigated. 2. Isoproterenol, epinephrine, norepinephrine, and phenylephrine produced positive chronotropic and inotropic effects. The relative potencies for the effects of these agents were: isoproterenol > epinephrine> norepinephrine> phenylephrine. Methoxamine had no effects or depressed the atria. 3. Pronethalol antagonized the positive effects of these adrenergic agents competitively. 4. Regitine did not affect the effects of these agents. 5. These data indicate that the adrenergic agents activate the atrial tissue of the frog via stimulation of adrenergic beta-receptor.