우울증에서 비침습적 두뇌 자극 치료

• 영문명: Therapeutic Application of Transcranial Magnetic Stimulation and Transcranial Direct Current Stimulation in Depression
• 발행기관: 대한신경정신의학회
• 저자명: 채정호(Jeong-Ho Chae)
• 간행물 정보: 『신경정신의학』제57권 제2호, 119~132쪽, 전체 14쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2018.05.31

영문 초록

Despite the fact that pharmacotherapy depressive disorders have proven efficacy, a substantial number of patients are resistant to conventional management. As neuroscientific research about pathophysiology of depression have accumulated, repeated transcranial magnetic stimulation(rTMS) and transcranial direct current stimulation (tDCS) have emerged as an important mechanism-based treatment modality. This overview provides a review of therapeutic application of rTMS and tDCS in patients with depression. The clinical and basic studies of rTMS and tDCS in depression were reviewed and integrated using a literature review and interview with experts. rTMS is a noninvasive procedure of a localized pulsed magnetic field to the surface of the head to cause a depolarization of neurons in the brain cortex. tDCS has a mechanism of modulating cortical excitability in a polarity-specific manner without eliciting action potentials. rTMS and tDCS seem promising for treating depression. Although therapeutic parameters and further technical improvement remain to be systematically investigated, rTMS and tDCS would be a safe and effective intervention to treat depression.

목차

서론

경두개 자기자극술(Transcranial Magnetic Stimulation, TMS)

경두개 직류 자극(Transcranial Direct Current Stimulation, tDCS)

결론

키워드

Repeated transcranial magnetic stimulation Transcranial direct current stimulation Depression.