수면무호흡증이 혈압에 미치는 영향

• 영문명: Effects of Sleep Apnea Syndrome on the Systemic Blood Pressure
• 발행기관: 대한신경정신의학회
• 저자명: 이희상 이성훈 조현상 남궁기 한승진 방승규
• 간행물 정보: 『신경정신의학』제36권 제1호, 113~121쪽, 전체 9쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 1997.01.30

영문 초록

Objects：This study was conducted to investigate the effects of sleep apnea syndromes on the systemic blood pressure. Methods：The subjects were 140 patients who were consulted to Yon-jung brain function and sleep research center for polysomnography due to snoring and sleep apnea from Jan. 1st 1995 to Oct. 31st 1995. Twenty-four out of 140 were excluded due to cardiovascular diseases other than systemic hypertension, antihypertensive medication, inadequate data or diagnosis other than sleep apnea syndrome. The remaining 116 were accepted as proper subjects. Using Pearson s correlation and multiple regression analysis, we looked for the relationship between sleep and respiratory variables to systemic blood pressure. Results：The results were as follows： 1) According to the correlation analysis, statistically significant variables to mean systolic and diastolic blood pressure were the total time and total number of sleep apnea, degree of oxygen saturation of total sleep time, apnea index, total time and total number of central apnea, and the total time of obstructive apnea. 2) According to the multiple regression analysis, only the total time of sleep apnea significantly affected mean systolic and diastolic blood pressure, and the degrees of affection were 7.9% and 6.2% respectively. Conclusion：These findings showed that sleep apnea syndrome had lower influence over systemic blood pressure than expected and regardless of the type, only the total time of sleep apnea influenced systemic blood pressure. In the case of central apnea, mechanisms other than hypoxemia and the increase of sympathetic activity during arousal may make it possible to increase systemic blood pressure.

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대상 및 방법

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키워드

Sleep apnea Blood pressure