한국 HIV감염자에서 생물학적 지표와 연관된 정신사회적 요인

• 영문명: Psychosocial Factors Associated with Biological Markers in Korean Patients with Human Immunodeficiency Virus Infection
• 발행기관: 대한신경정신의학회
• 저자명: 이상혁 고경봉 김준명 홍성관 최태규 이은희 서신영
• 간행물 정보: 『신경정신의학』제45권 제1호, 34~41쪽, 전체 8쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2006.01.30

영문 초록

Objectives：The purpose of this study was to identify psychosocial factors associated with biological markers in Korean patients with human immunodeficiency virus (HIV) infection. Methods：50 patients with HIV infection were enrolled. We administered Stress Response Inventory (SRI), the Coping Scale, and the Korean version of Smithklein Beecham quality of life scale (QOL) to the 50 patients and measured CD4+ cell count and HIVRNA copies. Results：Simple correlation analysis showed significant correlation between psychosocial factors and CD4+ cell count. Tension, aggression, depression, frustration subscale in SRI and distancing, self controlling in coping scale had negative correlation with CD4+ cell count, whereas QOL showed positive correlation. Multiple regression analysis showed significant negative association between distancing and CD4+ cell count. There were no differences in CD4+ cell count and HIVRNA between homosexual patients and heterosexual patients. However, aggression, confrontation in SRI, and distancing in coping scale scored significantly higher in heterosexual patients than homosexual patients. Conclusion：These results suggest that CD4+ cell count may be associated with psychosocial factors in Korean patients with HIV infection, and passive coping strategy like distancing may be one of important factors in the progression of HIV infection. These findings also suggest that psychosocial intervention programs are needed for Korean patients with HIV infection.

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키워드

HIV Stress CD4+ cell count Coping strategy