정신분열병의 유전적 고위험군에서 인지, 정서 및 사회기능 연구

• 영문명: Cognition, Emotion & Social Function：Are Vulnerability Markers for Developing Schizophrenia?
• 발행기관: 대한신경정신의학회
• 저자명: 이경진 위휘 유소영 이애라 송지연 하태현 홍경수 김명선 권준수
• 간행물 정보: 『신경정신의학』제45권 제1호, 3~10쪽, 전체 8쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2006.01.30

영문 초록

Objectives：Vulnerability marker in biological relatives of schizophrenia may be very useful in identifying the propensity for the development of schizophrenia. This study suggests that the relatives at risk for genetically developing schizophrenia have impairments in several domains of cognition, social function and affective function as a vulnerability marker. Methods：A neurocognitve function test, a social function test and an affective function test were administered to fifteen healthy relatives from families with two or more patients with schizophrenia (geneticallly high risk subjects). Fifteen healthy controls matched for age and gender were recruited in this study. Results：Compared to the control subject, the genetic high risk subjects performed significantly more poorly in the selective attention and recall memory of neurocognitive function. The high risk subjects also had lower scores in independence-performance and independence-competence of the social function test and emotion control of the affective function test. Conclusion：Selective attention, recall memory, independence-performance, independence-competence and emotion control ability may be a valuable marker for genetic study of schizophrenia.

목차

서 론

방 법

결 과

고 찰

REFERENCES

키워드

Schizophrenia Genetic high risk Neurocognitive function Selective attention Recall memory Independence-performance Independence-competence Emotion control