정신과 외래에서 향정신성약물을 복용 중인 환자에서의 하지불편증후군

• 영문명: Restless Legs Syndrome in Psychiatric Outpatients with Psychotropic Agents
• 발행기관: 대한신경정신의학회
• 저자명: 지구덕 한승희 양명성 양창국
• 간행물 정보: 『신경정신의학』제46권 제4호, 391~397쪽, 전체 7쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2007.07.30

영문 초록

Objectives：The purpose of this study was to investigate the clinical characteristics and incidence of restless legs syndrome (RLS) in outpatients with psychiatric illness. Methods：146 adult patients (male 52, female 94) were selected from those who visited a psychiatric outpatient clinic. RLS was evaluated through an interview method using diagnostic criteria and a severity rating scale for RLS developed by the International RLS Study Group (IRLSSG). The authors also applied Beck’s Depression Inventory (BDI), Beck’s Anxiety Inventory (BAI), the Pittsburgh Sleep Quality Index, Barnes Akathisia Rating Scale and neurological examination. Results：Thirty-four (23.3%) among 146 subjects were diagnosed as having RLS. Fifteen (44.1%) among those 34 RLS patients reported to have developed their RLS after starting their psychotropic agents and only 4 patients (11.7%) had currently been receiving treatment for their RLS. The RLS group showed higher BDI and BAI scores (p<0.01) and lower sleep quality (p<0.01) compared to those of non-RLS. The RLS group also showed a significantly higher co-morbidity of parasomnias (χ2=8.5, p<0.01) and peripheral neuropathy (χ2=5.2, p<0.05). Conclusion：The results from this study suggest that a substantial proportion of outpatients with psychiatric illness are suffering RLS. Our data suggest that clinicians should pay attention to the possible presence of RLS among their patients who are taking psychotropic agents.

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키워드

Restless legs syndrome Psychiatric patients Incidence Clinical characteristics