양극성 장애 환자의 첫 삽화에 따른 임상적 특징

• 영문명: Clinical Features Related to First Episode Polarity in Bipolar Disorder
• 발행기관: 대한신경정신의학회
• 저자명: 김윤기 이은 전덕인 유빈 석정호 조현상 김세주
• 간행물 정보: 『신경정신의학』제46권 제4호, 352~356쪽, 전체 5쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2007.07.30

영문 초록

Objectives：It has been reported that first episode polarity affected the course and the prognosis of bipolar disorder. However, there is remarkable paucity of information regarding first episode polarity in bipolar disorder. We investigated the clinical characteristics related to the first episode polarity of bipolar patients who had been hospitalized. Methods：Analyses were based on the medical documents of 520 bipolar patients who had been hospitalized in 4 hospitals. We examined clinical features of the current episode, demographics, past treatment history, suicidal attempt history, family history and comorbidity. Clinical characteristics were compared between manic onset and depressive onset patients. Results：The mean age of the patients was 36.7 years old；they had 2.1 number of admission history and 6.6 years of illness duration. The patients beginning with depressive onset was 39.4%, and they had more diagnosis of bipolar II disorder, more number of suicidal attempts and reported more depressive mood during index admission than manic onset patients. Conclusion：Depressive onset is a common presentation in bipolar disorder. It is necessary to give more attention to depressive episode in bipolar disorder. Prospective study needs to explore the correlation of first-episode of polarity and course of the illness in the future.

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키워드

Bipolar disorder Clinical characteristics First episode