자기공명영상에서 뇌실주위 백질연화증을 보인 정신분열병 1예

• 영문명: A Case of Schizophrenia with Periventricular Leukomalacia on Magnetic Resonance Imaging
• 발행기관: 대한신경정신의학회
• 저자명: 이문인 신혜랑 김학렬 박상학 김상훈
• 간행물 정보: 『신경정신의학』제49권 제2호, 256~259쪽, 전체 4쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2010.03.30

영문 초록

Schizophrenia was once known as a functional psychosis, a disorder with no structural basis. However, nowadays research has identified and confirmed many structural abnormalities in schizophrenia. One prominent such feature is the combination of ventricular enlargement and decreased cerebral volume. Periventricular leukomalacia causes cerebral palsy, cognitive impairment, visual impairment, and seizures. Recent studies reveal that periventricular leukomalacia causes ventricular enlargement and many brain circuit disruptions. Ventricular enlargement caused by periventricular leukomalacia is the most common pathological marker of schizophrenia. In this study, we report a case with periventricular leukomalacia on MRI findings in a 28-year-old schizophrenia patient. This patient showed auditory hallucinations and somatic delusions. We highlight the structural abnormalities, especially periventricular leukomalacia, in this case of schizophrenia.

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키워드

Periventricular leukomalacia Magnetic resonance imaging Schizophrenia