Apathy : 개념의 변화와 전망

• 영문명: Apathy : Conceptual Change and Future Direction
• 발행기관: 대한신경정신의학회
• 저자명: 송후림 박원명
• 간행물 정보: 『신경정신의학』제50권 제5호, 354~361쪽, 전체 8쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2011.09.30

영문 초록

Apathy is a common problem observed in many neuropsychiatric disorders. In the past, apathy was a conventional term that designated an absence of feeling and a flattening of affective responses. But recent research has produced the concept that the core feature of apathy is a lack of motivation and manifests as diminished goal-directed behavior, cognition, and emotion, including initiation and responsiveness deficiency. Now, apathy tends to be considered as a distinct clinical symptom and syndrome, but it is still conceptually ill-defined and there is no definite consensus on diagnostic criteria. Several rating scales such as the Apathy Evaluation Scale (AES) and Apathy Scale (AS) have been developed that assist in making a diagnosis of apathy and a measurment of severity. Neuroimaging studies have indicated that apathy is primarily a dysfunction of the frontal-subcortical system, which is called the motivational circuit, and can be divided into auto-activation, cognitive, emotional subtypes by various frontal-subcortical circuits which have been damaged. Dopamine (DA) and acetylcholine (Ach) have important roles in this area. Many studies have focused on the relationship between apathy and depression. The core feature of apathy is distinguished from depression, but they share too many incidental aspects to be divided off completely. It is because the diagnostic criteria of depression had developed before the new concept of apathy was proposed, so symptoms of apathy were included in the diagnostic criteria of depression. There is a need for consensus of definition and diagnostic criteria of apathy to facilitate future research, which may be able to get at the root of other neuropsychiatric disorders such as depression

목차

서 론

Apathy의 역사적 개념

Apathy의 새로운 개념

Apathy의 평가 도구

Apathy의 신경생물학적 모델

Apathy와 우울증

결 론

REFERENCES

키워드

Apathy Motivation Goal directed behavior Responsiveness Depression