精神分裂病의 構造的 腦 變化

• 영문명: Structural Brain Changes in Schizophrenia
• 발행기관: 대한신경정신의학회
• 저자명: 田珍淑
• 간행물 정보: 『신경정신의학』제32권 제3호, 309~318쪽, 전체 10쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 1993.05.30

영문 초록

The evidences of structural abnormalities in schizophrenic brains could be supported by the morphological and functional neuroimaging techniques as well as the neuropathological findings of the postmortem brains of schizophrenic patients. Gliosis and cellular dysarray, in addition to the tissue atrophy induced by the neuronal loss, in limbic system, basal ganglia, cerebral corticies and other brainstem structures were reported in the literature. The causes o f structural brain abnormalities in schizophrenia are not yet clarified. Some hypotheses include genetic effects, perinatal brain injury, and developmental anomaly and embryonic insult with viral infection which affects N-CAM maturation changes during reinnervation o f injured neuronal cells to result in cellular disarray.

목차

서 론

정신분열병 환자 뇌의 구조적 이상

구조적 뇌 변화의 의미

요 약

References

키워드

Schizophrenia Brain atrophy Gliosis Cellular disarray Developmental anomaly