정신분열증 환자의 기억력

• 영문명: Memory Function in Patients with Schizophrenia
• 발행기관: 대한신경정신의학회
• 저자명: 이홍식 전덕인
• 간행물 정보: 『신경정신의학』제34권 제3호, 625~635쪽, 전체 11쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 1995.05.30

영문 초록

This paper reviews the literature on memory function in patients with schizophrenia. It has been repeatedly reported that schizophrenic patients display memory deficits when compared to other psychiatric populations and to normals. Asynthesis of findings indicates that both verbal and visual memories, especially recall task perform ance, are affected negatively, an d the abnorm alities of both temporal lobe structures including the hippo campus are proposed. M oreover, imaging studies of the brain and postm ortem studies confirm this possibilities. R esearchers over the years believed that deficits in encoding and retrieval process characterized the memory dysfunctions found in the schzophrenic patients. However, m ore recent studies showed that the dysfunction might be associated with im pairem ent of recognition in chronic schizophrenics. In comparison with the normals, schizophrenic patients show ed decreased functioning in free recall task perform ance w here highly elaborated encoding skills and memory strategies are needed. Previously, it has been believed that memory dysfunctions in patients with schizophrenia were secondary to attention deficits they possessed, but recent findings enhance the possibility that memory dysfunctions found in the schizophrenics is somew hat fundamental, which is to conclude that memory dysfunctions are due to the biological abnorm alities of the disease rather than a secondary phenomenon to attention deficit they have. The effect of antipsychotics on memory functions is still controversial. On the contrary, the effect of anticholinergics on memory function is clearly adverse that more attention to anticholinergics would seem warranted, at least insofar as the study of memory in schizophrenia is concerned.

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키워드

Schizophrenia Memory function Tem poral lobe structure Antipsychotics Anticholinergics