전쟁관련 외상후 스트레스장애 환자에서 Dexamethasone Suppression Test 소견

• 영문명: Dexamethasone Suppresion Test Findings in Patients with Combat-related Posttrauma tic Stress Disorder
• 발행기관: 대한신경정신의학회
• 저자명: 정혜경 정문용 정용진
• 간행물 정보: 『신경정신의학』제35권 제6호, 1459~1466쪽, 전체 8쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 1996.11.30

영문 초록

In order to investigate the possibility of enhanced negative feedback sensitivity of the hypothalamic-pituitary-adrenal axis, we used dexamethasone suppression test in 12 male posttraumatic stress disorder patients and age matched 12 male controls. We also measured Mississippi scale and Beck depression inventory(BDI), which were significantly higher in patient group than in control group. There was no difference in combat exposure scale(CES) score and baseline plasma cortisol level between patient group and control group. Plasma cortisol levels at 8 ： 00 a.m. and 4 ： 00 p.m. were significantly lower in patient group than control group. Relative value o f change was significantly higher in patient group than in control group. There was no significant correlation between relative value of change of cortisol from baseline to 4 ： 00 p.m. and B D I and CES sores. But Mississippi scale score had significant correlation with relative value of change. It is supposed that alteration of DST observed in this study be related with enhanced H PA axis sensitivity in posttraumatic stress disorder.

목차

서 론

대상 및 방법

결 과

고 찰

요 약

참고문헌

키워드

Posttraumatic stress disorder Dexamethsone suppression test Cortisol Hypothalamic-pituitary-adrenal axis