조증환자에 있어서의 Carbamazepine의 효과에 대한 연구

• 영문명: The Effects of Carbamazepine on the Manic Patients
• 발행기관: 대한신경정신의학회
• 저자명: 김승혜 이병윤
• 간행물 정보: 『신경정신의학』제27권 제1호, 67~79쪽, 전체 13쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 1988.02.28

영문 초록

The authors have studied on the antimanic and hematological effects of carbamazepine on twenty cases of manic patients. Thirteen of twenty manic patients showed rather favorable responses, from moderate to marked degree. Significant decreases on the BPRS(Brief Psychiatric Rating Scale) and Ms (Mania-State Rating Scale) score appeared as fast as within three days after starting carbamazepine treatment. Carbamazepine was found to cause statistically significant, but clinically insubstantial, decreases in white cell indexes. The consistent decreases in white cell counts observed withcarbamazepine treatment should be differenctiated from the extremely rare, idiosyncratic blood dyscrasias previously reported in the literatures. There were no significant side effects except two cases of dropout during carbamazepine treatment. These results suggest that carbamazepine is useful in treating manic patients.

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