Antioxidant potential and characterization of Moringa Oleifera leaf extract through multi-method screening Most

• 발행기관: 한국예방수의학회
• 저자명: Most Nusrat Zahan Donghyeon Lee Jimin Park Sobin Jeon Ye Rin Kim Il Rae Rho Euikyung Kim Changkeun Kang
• 간행물 정보: 『Journal of Preventive Veterinary Medicine』Vol.48, No.4, 279~288쪽, 전체 10쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2024.12.31

국문 초록

Moringa oleifera, a versatile plant, has been traditionally used to treat various ailments and is gaining scientific attention due to its potential as a medicine. Native to the Indian subcontinent, it is widely grown in tropical and subtropical regions, thriving in Asia, Africa, and South America, especially in arid climates. This study explores the antioxidant potential of Moringa oleifera leaf extract (MOLE), employing a comprehensive screening approach with various solvents to identify the most effective extraction method. Initial experiments assessed antioxidant efficacy and yield using distilled water (D.W.), 95% ethanol, and 95% methanol. Among these, 95% ethanol extract demonstrated superior antioxidant activity, confirmed through assays such as 2,2-diphenyl-1-14 picrylhydrazyl (DPPH) radical scavenging assay, total polyphenol content analysis, and reducing power assay. In addition, with the 95% ethanol MOLE, a higher extraction efficiency was yielded compared to other solvents, making it the most effective for large-scale preparation. HPLC analysis revealed the presence of key bioactive compounds, including ellagic acid, rutin, Q-3-O, quercetin, and kaempferol. Results revealed that MOLE, prepared using 95% ethanol, exhibited remarkable antioxidant properties, attributed to its rich polyphenolic content. This research underscores the therapeutic potential of MOLE as a natural antioxidant source and highlights the importance of solvent optimization in phytochemical extractions.

목차

INTRODUCTION

MATERIALS AND METHODS

RESULT

DISCUSSION

REFERENCES

키워드

Antioxidant activity Moringa oleifera HPLC analysis Phytochemical extractions Polyphenol

참고문헌

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