신장과 체중의 변화가 사구체 여과율에 미치는 영향

• 영문명: A Study on How Height and Weight Affects Glomerular Filtration Rate
• 발행기관: 대한핵의학기술학회
• 저자명: 박아랑(A Rang Park) 최종숙(Jong Sook Choi) 이영희(Young Hee Lee) 정우영(Woo Young Jung)
• 간행물 정보: 『핵의학기술』Vol.23 No.1, 40~44쪽, 전체 5쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2019.04.30

영문 초록

Purpose Glomerular filtration rate (GFR) is an important index for evaluation of renal function, renal disease diagnosis and progress monitoring. Therefore, accurate measurement of GFR is clinically important. Among the factors that affect the GFR result, there have been many discussions on the methods such as the correction of the kidney depth, net syringe count, and the method of setting the ROI. However there has been no consideration of counting in the most basic factors like height and weight measurement. In this study, we investigate how height and weight changes affects the result of GFR and review the importance of standardized body measurements. Materials and Methods Fifty patients who underwent GFR test were randomly sampled and examined for changes in height and body weight within one month. From the normal patients without renal disease to the patients with severely decreased GFR, we applied the GFR formula of Gate with varying height and weight. Results: The result showed variation of the height at maximum three centimeters and six kilograms of weight. The first calculation of GFR was done with fixed height value and control variable as weight. Weight was incremented by one kilogram each time up to six kilograms. The GFR showed increased result with increasing weight. The result of GFR showed ten percent increase with six kilograms of weight increase. On the other hand, when height value was incremented by one centimeter up to three centimeters showed decreased GFR result with fixed weight value. Up to three centimeters of height increase showed two percent of decreased GFR with fixed weight. Conclusion This study showed varying GFR result when height and weight changes. Therefore it is clinically crucial not only to maintain and manage body measuring instrument but also to have a standardized measurement methods to derive accurate measured values and to achieve reproducibility.

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실험재료 및 방법

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키워드

Glomerular filtration rate(GFR) Standardization Body measurements