대뇌 신경 교종 18F-FDG PET/CT 검사에서 포도당 부하 기법에 대한 고찰

• 영문명: A Discussion on Glucose Loading Method in 18F-FDG PET/CT for Cerebral Gliomas
• 발행기관: 대한핵의학기술학회
• 저자명: 최용훈(Yong-Hoon Choi) 박민수(Min-Soo Park) 임한상(Han-Sang Lim) 김재삼Jae-Sam Kim
• 간행물 정보: 『핵의학기술』Vol.27 No.1, 53~57쪽, 전체 5쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2023.05.30

영문 초록

Purpose: The purpose of this study is to determine whether the glucose loading method (GLM) is useful in the differentiation of cerebral gliomas by comparing it with fasting images. Materials and Methods: The patients were 70 people diagnosed with cerebral gliomas, and the equipment was Discovery 710 (GE Healthcare, MI, USA). All patients fasted for more than 6 hours, and fasting images and GLM were performed under the same imaging conditions, and the examination interval was 1 to 14 days. GLM administered 250 ㎖ of 10% glucose solution prior to radiopharmaceutical injection. SUVmax of cerebral glioma and SUVmean of cerebral cortex were measured and then compared and analyzed by tumor-to-normal brain cortex ratio (TNR). Statistical analysis confirmed the difference between the two images with an independent-sample t-test. Results: The averages of GLM and fasting TNR were 1.26 and 1.09, respectively, which were 15.6% higher in GLM. In low-grade, the difference in TNR was insignificant at 4%, but in high-grade, 23%, GLM was high. There was a statistically significant difference between the two images (P=0.008), but there was no statistically significant difference in TNR in the low grade (P=0.473), and there was a very significant difference in the high grade (P=0.005). Conclusion: GLM increased TNR for cerebral gliomas. In particular, it was found that the TNR increased more in the high grade. Therefore, GLM is considered to be useful for the differentiation of high-grade gliomas.

목차

서론

실험재료 및 방법

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결론

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키워드

GLM TNR High-Grade