PET/CT 검사에서 환자체형에 따른 적정검사 프로토콜에 관한 고찰

• 영문명: Study to Protocol of PET Acquisition Time for Patient Body Type in PET/CT
• 발행기관: 대한핵의학기술학회
• 저자명: 조석원(Seok Won Cho) 함준철(Joon-Chul Ham) 강천구(Chun Goo Kang) 반영각(Young Kag Bahn) 이승재(Seung Jae Lee) 임한상(Han Sang Lim) 이창호(Chang-Ho Lee) 박훈희(Hoon-Hee Park)
• 간행물 정보: 『핵의학기술』Vol.17 No.2, 72~77쪽, 전체 6쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2013.11.30

영문 초록

Purpose: Whole-body PET using radiopharmaceutical is one of the imaging study methods for physiological changes of body. High specificity of the PET-CT examination is used to detect an early stages of cancer and metastatic cancer by imaging a physiological changes. During the imaging process;PET image has been characterized by a relatively low image quality due to its low sensitivity and the acquisition of random and scatter coincidences as well as patients figure. Therefore;the image quality as the changes of the acquisition times of patient weight was evaluated in this study. Materials and Methods: Thirty patients who presented to our hospital were enrolled. They were divided to normal;overweight;and obese group using BMI index;respectively. The patients with a liver disease and diabetes were excluded. ¹⁸F-FDG was administered to the patients as 5.2 MBq per kg. After an hour from an injection;image acquisition was obtained as List mode in a part of liver in 1 bed. SNR (signal-to-noise ratio) of each groups acquisition times were confirmed from the calculated radiation counts and random fractions. The statistical significance of three groups was confirmed through one-way ANOVA test. On the basis of the counts of 2 minutes on normal group;the SNR of overweight group and obese group were compared. Results: The SNR were increased with loger aquisition time in 3 groups. In the condition of same acquisition time;the SNR had a statistical significance (P<0.05). The SNR were decreased to the normal;overweight;and obese;respectively. Liver activity had no significance difference on each group and RF had the significance differences (P<0.05). On the basis of the counts of 2 minutes on normal group;there were no statistical significance in a three minute acquisitions of overweight group and two minute acquisitions of obese group (P=0.150). Conclusion: In this study;the administrated amount of radiation dose did not adjust as the change of the patients weight. Increasing the acquisition time when the administration of the same amount of dose was able to get a good result of SNR. When the Based 2 minute on normal group;if overweight and obese case the increased acquisition time of 3 minute was able to obtain a similar SNR. On the basis of the normal group;the acquisition times of overweight and obese group were increased to 3 minutes per bed and the SNR were similar to the normal group.

목차

서론

대상 및 방법

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키워드

SNR, BMI