This study aimed to examine the effect of psychological and physical job demands perceived by airline cabin crew on the subjective health status and subjective well-being of flight attendants. did In particular, by examining the effect of perceived job demands of airline cabin crew, whose turnover rate increases due to job demands, on their subjective health status and subjective well-being, this study aimed to identify the direction airlines should pursue in a rapidly changing competitive environment. Specifically, this study examined the effect of perceived psychological and physical job demands on subjective health status and subjective well-being, the effect of subjective health status on subjective well-being, and the mediating effect of subjective health status among flight attendants. In order to test such an effect relationship, the causal effect relationship between factors was tested with the SPSS Process Macro model. As a result of the study, it was tested that the perceived psychological and physical job demands of flight attendants had a negative effect on the subjective health status of flight attendants. In addition, it was confirmed that the subjective health status of flight attendants had a positive effect on subjective well-being. In particular, it was found that subjective health status had an indirect effect on the relationship between psychological and physical job demands on subjective well-being via subjective health status, suggesting empirical grounds for interpreting the importance of subjective health status. This study suggests the importance of human resource management by examining the effect of flight attendants' perceived job demands on subjective well-being, ultimately increasing flight attendants' job satisfaction, and suggesting specific airline management strategies and ways to improve competitiveness.