유산균 R&B Balance？瑛？ 대장염 억제 효과

• 영문명: Anti-colitic Effect of Lactic Acid Bacteria R&B Balance？？
• 발행기관: 한국유산균프로바이오틱스학회
• 저자명: 안영태(Young-Tae Ahn) 이호용(Hoyong Lee) 이정희(Jung-Hee Lee) 김동현(Dong-Hyun Kim) 허철성(Chul-Sung Huh)
• 간행물 정보: 『Current Topics in Lactic Acid Bacteria and Probiotics』Current Topics in Lactic Acid Bacteria and Probiotics 1권 1호, 70~78쪽, 전체 9쪽
• 주제분류: 농수해양 > 식품과학
• 파일형태: PDF
• 발행일자: 2013.01.30

영문 초록

The anti-colitic effect of lactic acid bacteria mixture (R&B Balance？？) consisting of Lactobacillus brevis HY7401, Lactobacillus helveticus HY7801 and Bifidobacterium longum HY8004 was investigated in dextran sulfate sodium (DSS)-induced colitic mice. Treatment with R&B Balance？？ reduced severe colitic symptoms, including colon shortening, myeloperoxidase (MPO) activity and malondialdehyde (MDA). The oral administration of R&B Balance？？ significantly reduced the activities of fecal chondroitinase and the fecal genotoxicity. Changes of fecal microflora in mice treated with DSS with or without R&B Balance？？ were assessed by terminal restriction fragment length polymorphism (T-RFLP). Cluster analysis of T-RFLP patterns demonstrated that microflora of DSS-induced colitic mice differed from that of normal mice and the oral administration of R&B Balance？？ could change the structure of gut microflora. These findings also suggest that R&B Balance？？ may improve colitis by inhibition of the production of harmful enzymes or toxic metabolites in intestine and influence the intestinal microbial diversity in DSS-induced colitic mice.

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anti-colitis dextran sulfate sodium lactic acid bacteria R&B Balance？？