구강건조증으로 강화된 안면부 염증성 통증 실험모델에서 계피와 강황의 병용효과

• 영문명: Efficacy of Combined Administration of Cinnamon and Curcumin on Acute Orofacial Inflammatory Pain Enhanced by Xerostomia
• 발행기관: 한국구강보건과학회
• 저자명: 최자형(Ja-Hyeong Choi) 남설희(Seoul-Hee Nam) 이민경(Min-Kyung Lee)
• 간행물 정보: 『한국구강보건과학회지』제9권 제4호, 40~46쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2021.12.30

영문 초록

Objectives: Orofacial pain can be caused by xerostomia, dental procedures, infections, and functional disorders in various areas, and it can greatly deteriorate patients’ quality of life. Thus, the present study aimed to investigate the efficacy of natural products in minimizing the side effects of synthetic drugs. Methods: In an experimental model of 4-DAMP-induced xerostomia, formalin was injected to induce inflammatory pain in the orofacial region, and the effects of oral administration of curcumin and cinnamon on pain behavioral response were observed. Results: In the experimental group with xerostomia, the pain response was prominent, which was suppressed in a concentration-dependent manner upon curcumin and cinnamon administration. Conclusions: Curcumin and cinnamon may be useful natural products for relieving the inflammatory orofacial pain caused by xerostomia.

목차

Ⅰ. 서론

Ⅱ. 연구방법

Ⅲ. 연구결과

Ⅳ. 고찰

Ⅴ. 결론

REFERENCES

키워드

Cinnamon Curcumin Natural products Orofacial pain Xerostomia