기능성 식품의 활성성분 함량에 따른 기능성 보고 모델 구축

• 영문명: Establishment of a Functional Reporting Model According to the Content of Active Ingredients in Functional Foods
• 발행기관: 대한약학회
• 저자명: 김석원(Suk Won Kim) 김선조(Sun Jo Kim) Nguyen Hoang Anh 정철운(Cheol Woon Jung) 권성원(Sung Won Kwon)
• 간행물 정보: 『약학회지』제65권 제4호(2021년), 321~330쪽, 전체 10쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2021.08.31

영문 초록

As the market of the functional foods is expanding to general foods, more efficient and accessible methods are required to provide quantitative and scientific evidences. In this study, we conceptualized and established a functional reporting model with logistic regression using the clinical data retrieved from the published literature. The model was validated with two active ingredients, vitamin E and lycopene. A search through PubMed using “tocopherol” or “tocotrienol” or “Vitamin E” as the keywords resulted in 45 data points corresponding to 35 studies in which the antiinflammatory efficacy of vitamin E was evaluated. The other search through PubMed using “lycopene” as a keyword resulted in 39 data points corresponding to 29 studies in which the antioxidant efficacy of lycopene was evaluated. We used C-reactive protein (CRP) or high sensitivity C-reactive protein (hs-CRP) as the inflammatory markers, and DNA damage, lipid, and protein oxidation for the measurement of antioxidant efficacy. According to our model, daily intake of at least 584.05 mg of vitamin E and 17.85 mg of lycopene is recommended to induce the functional effects. In conclusion, we anticipate that this approach to the functional report modeling would greatly expand the market of functional foods, especially for the native crops.

목차

서 론(Introduction)

방 법(Methods)

결과 및 고찰(Results and Discussion)

결 론(Conclusion)

감사의 말씀(Acknowledgment)

Conflict of Interest

References

키워드

Logistic regression Vitamin E Lycopene Functional food