어린이제품 내 프탈레이트류 및 대체제의 규제와 독성자료에 대한 연구

• 영문명: Regulation of Phthalates and Their Alternatives in Children’s Products and Their Toxicity Data
• 발행기관: 한국환경보건학회
• 저자명: 이인혜(Inhyae Lee) 나진성(Jinsung Ra) 지경희(Kyunghee Ji)
• 간행물 정보: 『1. 한국환경보건학회지』제47권 제1호, 1~19쪽, 전체 19쪽
• 주제분류: 공학 > 환경공학
• 파일형태: PDF
• 발행일자: 2021.02.28

영문 초록

Objectives: Phthalates, which are widely used as plasticizers, have been recognized as endocrine disruptors. In the present study, we provided information on the regulation of these chemicals and summarized the information available on their detection and toxicity in children’s products and those of their alternatives. Methods: The regulatory frameworks related to phthalates in children’s products in Korea, the United States (US), and the European Union (EU) were compared. Data on the detection concentration of 16 phthalates and seven phthalate alternatives that could be used in polyvinyl chloride (PVC) plastic products for children as well as on their toxicity classification and endocrine disruption toxicity were collected from the literature. Results: Korea adopted US and EU chemical standards for six phthalates (DEHP, BBP, DBP, DINP, DIDP, and DNOP), but not others (e.g., DIBP, DPP, DHP, and DCHP). Among the ten phthalates and seven substitutes for which regulatory standards were not determined, DIBP, DHP, DEHA, DIBA, DINA, and DEHT were detected in children’s products made from PVC plastic. DIBP and DHP, which have a reproductive toxicity classification of 1B, were frequently detected in PVC toys. The reproductive toxicity, estrogenicity, and anti-androgenic activity of the unregulated phthalates and their alternatives have been reported in diverse in vitro and in vivo assays. Conclusion: The use of unregulated phthalates and their substitutes in children’s products is increasing. Further monitoring and toxicological information on phthalate alternatives is required to develop proper management plans.

목차

I. 서 론

II. 연구 방법

III. 연구결과 및 고찰

IV. 결 론

키워드

Adipates children’s products endocrine disruption phthalates terephthalates