깔라몬딘오렌지로부터 집속초음파추출을 이용한 기능성 물질 생산 공정 최적화

• 영문명: Process Development for Production of Functional material from Citrus Madurensis(Citrofortunella microcarpa) Using Innovative Extraction by Focused Ultrasound(INEFU).
• 발행기관: 한국자원식물학회
• 저자명: 서승범(Seo, Seung beom) 김유미(Kim, Yu Mi)
• 간행물 정보: 『한국자원식물학회 학술심포지엄』2018년도 추계학술대회, 94~94쪽, 전체 1쪽
• 주제분류: 농수해양 > 기타농수해양
• 파일형태: PDF
• 발행일자: 2018.10.31

영문 초록

In this study, we investigated the effect of branch extracts from Vaccinium oldhamii (VOB) on melanin synthesis in B16F10 cells. VOB promoted melanin production in absence or presence of ${\alpha}$-melanocyte-stimulating hormone (${\alpha}-MSH$) in B16F10 cells. However, VOB did not affect the expression of tyrosinase and TRP-1 associated with melanin synthesis at the mRNA and protein level in B16F10. But, VOB decreased TRP-2 protein level and induced tyrosinase activation in B16F10 cells. Inhibition of tyrosinase activity and tyrosinase knockdown attenuated VOB-mediated melanin synthesis. In conclusion, it is thought that VOB may stimulate melanin synthesis through activating tyrosinase activity.

키워드

Melanin Melanogenesis Tyrosinase activity Vaccinium oldhamii