저온숙성한 한방혼합 가수분해물의 자가포식에 의한 항노화 증진 효과

• 영문명: Effects on Anti-aging Induced by Autophagy of Herbal Mixture Hydrolyzed Extract Ripened at Low Temperature
• 발행기관: 한국인체미용예술학회
• 저자명: 조현대(Hyun-Dae Cho) 강정욱(Jung-Wook Kang) 성미경(Mi-Kyung Sung) 최호민(Ho-Min Choi) 조미래(Mi-Rae Jo) 유단희(Dan-Hee Yoo) 김정환(Jeung-Hoan Kim) 조항의(Hang-Eui Cho) 이인철(In-Chul Lee)
• 간행물 정보: 『한국인체미용예술학회지』한국인체미용예술학회지 제21권 제4호, 249~260쪽, 전체 12쪽
• 주제분류: 예술체육 > 예술일반
• 파일형태: PDF
• 발행일자: 2020.12.20

영문 초록

In this study, we investigated the anti-aging effects related autophagy of herbal mixture hydrolyzed extract ripened at low temperature. We were confirmed to the hydrolyzed proteins in the herbal mixture extract through SDS-PAGE. Comparing the skin efficacy according to the extracts, the hydrolyzed extract ripened at low temperature inhibited the matrix metalloproteinase-1 (MMP-1) expression than the water extract, and the procollagen type 1 production promotion ability was also excellent. The autophagy effects of hydrolyzed extract was increased the expression of ATGs and LC3 genes activity. It was confirmed to be the decrease of MMP-1 expression treated Bafilomycin A1 exposure. We were also inhibited the senescence of skin cells by beta-galactosidase staining. Therefore, the herbal mixture hydrolyzed extract at low temperature is expected to be widely used as anti-aging effects on autophagy in cosmetic material for the skin.

목차

Ⅰ. 서론

Ⅱ. 재료 및 방법

Ⅲ. 결과 및 고찰

Ⅳ. 결론

참고문헌

키워드

가수분해물 저온 자가포식 항노화 화장품 Hydrolyzed Extract Low Temperature Autophagy Anti-aging Cosmetics