살균제 folpet의 변이원성에 관한 연구

• 영문명: Mutagenicity test of the fungicide folpet
• 발행기관: 한국예방수의학회
• 저자명: 김재훈(Jae Hoon Kim) 윤용덕(Yong Dhuk Yoon) 황의경(Eui Kyung Hwang) 진영화(Young Hwa Jean)
• 간행물 정보: 『Korean Journal of Veterinary Public Health』Vol.17, No.3, 339~344쪽, 전체 6쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 1993.12.30

영문 초록

Folpet, a fungicide with widespread application in agriculture in Korea, was examined for mutagenicity by Ames’ test using Salmonella typhimurium mutants(TA100, TA98, TA1535 and TA 1537). Folpet caused mutagenicity for all 4 strains without addition of S-9 mix and mutagenic activity was generally reduced by the S-9 mix. Mutagenic activity of the folpet was observed from a dose of 5㎍/plate concentration for TA1537, TA98 and TA100 strains, and 10㎍/plate for TA 1535, respectively. Toxic activity of the folpet was observed from a dose of 100㎍/plate for all Salmonella typhimurium strains.

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키워드

Folpet mutagenicity Ames’ test Salmonella typhimurium