韓國에서 츄잔病의 發生 및 binary ethylenimine 不活化 츄잔바이러스 豫防藥의 소에서의 免疫原性 試驗

• 영문명: An outbreak of chuzan disease in Korea and the immunogenicity of binary Ethylenimine-treated chuzan virus vaccine in cattle
• 발행기관: 한국예방수의학회
• 저자명: Bong Kyun Park(朴奉均) Jae Chin Rhee(李在鎭) Soo Hwan An(安壽煥) Ho Kyou Moon(文琥奎) Kong Sik Kim(金恭湜) Dong Soo Son(孫東秀) Kwang Won Lee(李光源)
• 간행물 정보: 『Korean Journal of Veterinary Public Health』Vol.17, No.3, 301~305쪽, 전체 5쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 1993.12.30

영문 초록

Chuzan disease of which the main clinical abnormalities were impairment of mobility and nervous signs took place in a calf breeding farm in Cheju province during the period of March, 1993. The serological survey indicated that antibody to Chuzan virus was present at a high rate in Cheju province, while it was at a low rate in the Honam area of the mainland. The retrospective sero-epidemiological investigations strongly suggested that Chuzan virus comes to Korea from the Southeast Asian countries and the first outbreak of Korea is simultaneous with that of Japan. A preliminary study for development of an inactivated Chuzan virus vaccine was performed. The binary ethylenimine treated-tissue culture fluid with a gel adjuvant had good immunogenicity in cattle. To control this disease in Korea, an inactivated Chuzan virus vaccine is scheduled for practical use in the field in the near future.

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Chuzan disease Sero-epidemiological investigations Inactivated vaccine Binary ethylenimine Immunogenicity