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학술논문

Epidemiological evaluation quality of life in patients suffering from early rheumatoid arthritis: a pragmatic, prospective, randomized, blind allocation controlled of a modular program group intervention

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영문명
발행기관
한국역학회
저자명
Hadi Yousefi Arvind Chopra Reza Farrokhseresht Sanjeev Sarmukaddam Fariba Asadi Noghabi Nilima Bedekar Abdolhosain Madani
간행물 정보
『Epidemiology and Health』37, 1~9쪽, 전체 9쪽
주제분류
의약학 > 면역학
파일형태
PDF
발행일자
2015.05.30
4,000

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OBJECTIVES: Epidemiology has taken on new roles in the management of health care services. In this study, we developed a non-pharmacological self-management modular program group intervention and evaluated its efficacy as an adjunct therapy in patients suffering from early rheumatoid arthritis (RA). METHODS: Patients were randomized to either participate in a non-equivalent intervention group along with the standard of care or only receive standard-of-care treatment at a community rheumatology center. The outcomes measured were a pain visual analog scale (VAS), patient general health (GH) on a VAS, and the Short Form 36 Health Survey version 2 scale measuring quality of life. These parameters were evaluated in the first week to obtain baseline values, and at 20, 32, 48, and 60 weeks to evaluate the efficacy of the intervention group. RESULTS: The patients were randomized, with 100 patients in the intervention group and 106 in the control group. The intervention and control groups were similar with regard to the percentage of women (86% vs. 89.6%), tobacco usage (25% vs. 19.8%), mean age (42.6±13.2 years vs. 46.6±10.9 years), and disease duration (15.3±6.7 months vs. 14.5±6.6 months). The mean outcomes were significantly different between the two groups, and post-hoc pairwise analysis demonstrated significant deterioration in the control group in contrast to improvement in the intervention group at the second, third, fourth, and fifth evaluations. Improvements were often seen as early as the 12-week and 24-week follow-up visits. CONCLUSIONS: Epidemiology contributes to the evaluation of how well specific therapies or other health interventions prevent or control health problems. The modular program group intervention implemented in this study appears to be a suitable and feasible method to facilitate much more comprehensive management of early RA in socioeconomically challenged communities.

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INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES

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APA

Hadi Yousefi,Arvind Chopra,Reza Farrokhseresht,Sanjeev Sarmukaddam,Fariba Asadi Noghabi,Nilima Bedekar,Abdolhosain Madani. (2015).Epidemiological evaluation quality of life in patients suffering from early rheumatoid arthritis: a pragmatic, prospective, randomized, blind allocation controlled of a modular program group intervention. Epidemiology and Health, 37 , 1-9

MLA

Hadi Yousefi,Arvind Chopra,Reza Farrokhseresht,Sanjeev Sarmukaddam,Fariba Asadi Noghabi,Nilima Bedekar,Abdolhosain Madani. "Epidemiological evaluation quality of life in patients suffering from early rheumatoid arthritis: a pragmatic, prospective, randomized, blind allocation controlled of a modular program group intervention." Epidemiology and Health, 37.(2015): 1-9

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