고해상능 전산화단층촬영을 이용한 폐기종 정량분석의 유용성

• 영문명: Usability of Emphysema Quantity Using High Resolution CT : In Comparison with Pulmonary Function Test
• 발행기관: 대한CT영상기술학회
• 저자명: 임상묵(Sang Muk Im) 이우식(Woo Sik Lee) 구양수(Yang Su Goo) 이강우(Kang Woo Lee) 조영기(Young Ki Cho) 강화원(Hwa Won Kang) 최창한(Chang Han Choi) 이광원(Kwang Won Lee) 김동수(Dong Su Kim)
• 간행물 정보: 『대한CT영상기술학회지』대한전산화단층기술학회지 제8권 제1호, 145~151쪽, 전체 7쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2006.04.30

영문 초록

Purpose The pathological severity of emphysema can be detected in high resolution CT well. We obtained mean lung density at inspiratory and expiratory, and percentage of emphysema subrange per slice through Quantitative emphysema CT. We tried to know the usability of Quantitative analysis in emphysema CT, the correlation between results of Quantitative emphysema CT and results of pulmonary function test such as forced vital capacity and forced expiratory volume in one second. Materials and Methods For this study, we selected 10 emphysema patients who had been found to have emphysema through high resolution CT and pulmonary function test during the period from june to august 2005, and who did not have accompanying diseases except emphysema. Also we selected 10 normal persons as a control group who did not have any history clinical disease or smoking in the past. In high resolution CT, we scanned the whole lungs on full inspiration and full expiration at slice thickness of 1mm and at intervals of 10mm using Somatom Sensation 16 with exposure conditions of 140kVp, 160mAs and algorithm B70 ultra sharp. In addition, we measured the area of emphysema by summing values obtained from each section through measuring the CT value inside the parenchyma of the lungs using a Quantitative CT software program. And calculated mean lung density and subrange percentage in the control group and the emphysema patient group on full inspiration and full expiration at pulmonary function test, and determined significance among them. Moreover, we compared forced vital capacity, which was an index of pulmonary function test for the emphysema patients, and forced expiratory capacity in one second for the emphysema patient group and analyzed significant differences using SPSS 10.0. Results Mean lung density of the emphysema patient group on full inspiration and that on full expiration were 895.59HU and 861.45HU, respectively, and their subrange percentages were 63% and 50%, respectively. Statistically significant differences were observed between the control group and the emphysema group in mean lung density and subrange percentage on full inspiration and full expiration. According to the result of analyzing the correlation of mean lung density and subrange percentage in the emphysema patient groups with the indexes of pulmonary function test such as forced vital capacity and forced expiratory volume in one second, statistically significant differences were observed in one second forced expiratory volume according to subrange percentage on full expiration. This suggests that quantative CT is a useful test for diagnosing emphysema and it is more effective to examine emphysema patients on full expiration. Conclusion According to the results of quantitative CT on the control group and the emphysema group, significant differences were observed between the groups in pulmonary function test, so the emphysema quantitative CT program appeared useful in analyzing emphysema but it is considered necessary to develop a pulmonary function quantitative CT that can examine patients with maintaining their breathing in a constant state.

목차

Abstract

Ⅰ. 목적

Ⅱ. 대상 및 방법

Ⅲ. 결과

Ⅳ. 고찰

Ⅴ. 결론

참고문헌

키워드

emphysema quantitative CT pulmonary function test mean lung density subrange percentage