염증성 호흡기 질환에서 기도점액 과다분비의 병태생리학적 의의 및 조절 방법 탐색

• 영문명: Pathophysiological Significance of Hypersecretion of airway Mucus in Inflammatory Pulmonary Disease and Investigation of Strategies of its Regulation
• 발행기관: 대한약학회
• 저자명: 이현재(Hyun Jae Lee)
• 간행물 정보: 『약학회지』제61권 제1호(2017년), 30~40쪽, 전체 11쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2017.02.28

영문 초록

Airway mucus is pivotal for physiological defense against invading particles, chemicals and pathogenic microbes. However, any abnormality of mucins can cause altered airway physiology and impair host defenses leading to severe diseases e.g. asthma and chronic obstructive pulmonary disease. Therefore, in this review, we discussed the recent progress in the field of research on the regulation of the gene expression, production and secretion of airway mucins, in order to make us try to develop the novel efficacious drug candidate for controlling the pathologic hypersecretion of airway mucins.

목차

기도 점액 과다분비 질환의 병태생리

기도 점액 과다분비 질환의 조절 방법론

기도 점액 과다분비 질환의 치료제 개발 전략

References

키워드

airway mucin hypersecretion regulation