이하선부에 발생한 Kimura’s disease에 대한 치험례

• 영문명: A CASE REPORT OF KIMURA’S DISEASE IN THE PAROTID REGION
• 발행기관: 대한구강악안면외과학회
• 저자명: 변성수(Sung-Soo Byun) 정휘동(Hwui-Dong Jung) 최영달(Young-Dal Choi) 김현실(Hyun-Sil Kim) 차인호(In-Ho Cha) 김형준(Hyung Jun Kim)
• 간행물 정보: 『대한구강악안면외과학회지』대한구강악안면외과학회지 제33권 제5호, 554~558쪽, 전체 5쪽
• 주제분류: 의약학 > 내과학
• 파일형태: PDF
• 발행일자: 2007.10.30

영문 초록

Kimura’s disease is a chronic inflammatory disorder presenting regional lymphadenopathy with painless soft tissue mass. Clinically, peripheral eosinophilia and elevated serum IgE levels are observed, and proteinuria associated with renal disease can also be present. Although its etiology is not clearly understood, it occurs predominantly in young Asian males and presents as a deep, subcutaneous mass involving salivary glands of the preauricular and submandibular regions. Spontaneous remission is very rare, and although treatments such as steroid, cytotoxic therapy and irradiation are available, chronic recurrence is very common. As such, surgical excision is regarded as the mainstay of therapy for localized lesions. Histopathologically, Kimura’s disease features eosinophilic abscsesses and dense lymphoid aggregates with germinal center. Clinical differential diagnosis of Kimura’s disease from other parotid diseases with accompanying lymphadenopathy is often very challenging prior to biopsy. The authors report a case of a 19-year-old male diagnosed with Kimura’s disease in the parotid region who underwent surgical excision and was followed up for 6 years, along with a review of related literature

키워드

Kimura disease Eosinophilia Lymphadenopathy IgE Angiolymphoid hyperplasia with eosinophilia