Risk Factors for Group B Streptococcus Colonization Among Pregnant Women in Korea

• 발행기관: 한국역학회
• 저자명: Eun Ju Kim Kwan Young Oh Moon Young Kim Yong Soo Seo Jung Hwan Shin Young Rae Song Jae Hyug Yang Betsy Foxman Moran Ki
• 간행물 정보: 『Epidemiology and Health』33, 1~7쪽, 전체 6쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 2011.01.30

영문 초록

OBJECTIVES: To identify obstetric and maternal factors related to Group B Streptococcus (GBS) coloniza-tion in pregnant women in Korea. METHODS: The study was conducted between the years 2006-2008 in four hospitals, Cheil and Eulji hospital in Seoul, and Motae and Eulji hospital in Daejeon. We recruited 2,644 pregnant women between 35 to 37 weeks of gestation who had visited for antenatal care. Participants completed a questionnaire, and urine, vaginal and rectal specimens were obtained and cultured using selective broth media. After delivery, medical records were reviewed. RESULTS: GBS colonization was significantly associated with hospital, age group, education, frequency of preg-nancy, and premature rupture of membranes (PROM, more than 18 hours). After adjustment for other vari-ables, Cheil hospital (odds ratio [OR], 2.05; 95% confidence interval [CI], 1.20-3.52), and the first pregnancy (OR, 2.32; 95% CI, 1.12-4.81) remained significant. History of vaginitis showed marginal significance (OR, 1.50; 95% CI, 0.98-2.29). CONCLUSION: To prevent GBS infection of neonates, clinicians should be alert to the potentially higher risk of GBS colonization in pregnant women in their first pregnancy, and women with pre mature rupture of mem-branes (PROM) (18 hours+) or who have a history of vaginitis.

목차

Abstract

INTRODUCTION

MATERIALS AND METHODS

RESULTS

DISCUSSION

REFERENCES

키워드

Colonization Pregnant women Risk factors Screening Streptococcus agalactiae