유리체강내 덱사메타손 삽입물 주입술 후 발생하는 안압상승에 대한 예방적 안압하강제의 효과

• 영문명: The Effect of Prophylactic IOP-Lowering Medication after Intravitreal Dexamethasone Implantation
• 발행기관: 대한안과학회
• 저자명: 한정빈 서경훈 유승영,Jung Bin Han, MD, Kyung Hoon Seo, MD, Seung-Young Yu, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume55,number12, 1828~1833쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2014.12.15

영문 초록

Purpose: To investigate the effect of prophylactic intraocular pressure (IOP)-lowering medication after intravitreal dexamethasone implantation. Methods: This is a retrospective analysis of 39 eyes undergoing intravitreal dexamethasone implantation for macular edema. Eyes were divided into two groups, those which had used prophylactic IOP-lowering medication and those which had not. IOP was measured preoperatively, at one week, and monthly until six months post-injection in each group. Results: The mean pre-injection IOP for the group that had not used prophylactic IOP-lowering medication and the group that had was 13.95 ± 3.32 mm Hg and 13.56 ± 3.71 mm Hg, the mean post-injection IOP at two months was 15.81 ± 3.75 mm Hg and 12.56 ± 5.02 mm Hg, and that at six months was 12.90 ± 2.95 mm Hg and 11.44 ± 3.59 mm Hg, respectively. The difference between the two groups was statistically significant at one week, one month, two months, and three months (p = 0.001, 0.002, 0.011, 0.035, respectively). A greater than 22 mm Hg increase in IOP was seen in four eyes (19.05%) in the group that had not used IOP-lowering medication and in one eye (5.56%) in the group that had. A greater than 5 mm Hg increase in IOP from baseline was seen in eight eyes (38.10%) in the group that had not used IOP-lowering medication and in one eye (5.56%) in the group that had. Conclusions: After intravitreal dexamethasone implantation, prophylactic IOP-lowering medication will significantly prevent IOP increase and decrease the number of patients requiring additional treatment that could cause potential damage to the retina and optic nerve.J Korean Ophthalmol Soc 2014;55(12):1828-1833

키워드

Intraocular pressure-lowering medication, Intravitreal dexamethasone implantation, Prophylactic use