결핵 뱀모양 맥락막염 환자에서 항결핵제와 스테로이드 치료 후에도 급격히 진행된 중심와 위축

• 영문명: Rapidly Progressing Foveal Atrophy with Tuberculous Serpiginous-Like Choroiditis Despite Combined Anti-Tuberculosis and Steroid Treatment
• 발행기관: 대한안과학회
• 저자명: 이진영 강건욱 신재필 김인택 박동호,Jin Young Lee, MD, Kun Wook Kang, MD, Jae Pil Shin, MD, PhD, In Taek Kim, MD, PhD,Dong Ho Park, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume54,number8, 1287~1292쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2013.08.15

영문 초록

Purpose: To report a case of rapidly progressing foveal atrophy with tuberculous serpiginous-like choroiditis. Case summary: A 54-year-old female patient had decreased vision of hand motions (os) for 3 days. Fundus examination showed optic disc swelling and yellowish chorioretinal lesions in the posterior pole (os). Optical coherence tomography (OCT) showed intraretinal edema and subretinal fluid in the left macula. Routine laboratory tests, serologic tests, and magnetic resonance imaging results were normal except for erythrocyte sedimentation rate (28 mm/hr). Fluorescein angiography showed the chorioretinal lesions appeared to be early hypofluorescence followed by late hyperfluorescence. Indocyanine green angiography showed hypofluorescence during early and late phases and the result of interferon-gamma release assay was positive. Under diagnosis of tuberculous serpiginous-like choroiditis, anti-tuberculous therapy combined with systemic corticosteroid was started. Despite decreased optic disc swelling, OCT showed a rapid progression of foveal atrophy within 2 weeks. Twelve weeks later, visual acuity was finger count at 10 cm. Six months later, best-corrected visual acuity and foveal atrophy were no interval change. Conclusions: Tuberculous serpiginous-like choroiditis with foveal involvement can show rapidly progressive foveal atrophy and poor visual prognosis.

키워드

Anti-tuberculous therapy, Foveal atrophy, Indocyanine green angiography, Interferon-gamma release assay, Tuberculous serpiginous-like choroiditis