약물에 의한 동공 확장이 안구, 각막 및 안내 수차에 미치는 영향

• 영문명: The Effects of Pharmacologic Pupil Dilatation on Ocular, Corneal, and Internal Aberrations
• 발행기관: 대한안과학회
• 저자명: 유은주 강수연 김효명 송종석,Eun Joo Yoo, MD, Su Yeon Kang, MD, Hyo Myung Kim, MD, PhD, Jong Suk Song, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume54,number4, 581~586쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2013.04.30

영문 초록

aberrations. Methods: Sixty-two right eyes of 62 healthy participants were included in the present study. Ocular, corneal and internal aberrations were measured with a KR-1W wavefront aberrometer (Topcon Corp., Tokyo, Japan) before mydriasis in mesopic conditions. After pupil dilatation with a mydriatic drug (phenylephrine chloride 0.5% + tropicamide 0.5%) (Mydrin-P, Santen, Osaka, Japan), the measurements were repeated. The wavefront data of 4-mm and 6-mm diameter zones were analyzed. The changes of aberrations before and after mydriasis were evaluated by paired t-test. Results: The values of ocular, corneal and internal spherical aberrations before and after mydriasis on the 4-mm diameter pupil zone were not statistically significantly different. On the 6-mm diameter zone, the ocular and internal spherical aberrations were statistically significantly different (p = 0.025, p = 0.002, respectively, paired t-test). However, the corneal aberrations did not show significant changes. The internal aberrations average before mydriasis was -0.043 (±0.21) μm and was shifted in a negative direction to -0.093 (±0.17) μm after mydriasis. The ocular aberrations average also changed toward negative after mydriasis. The high-order aberrations and astigmatism did not change significantly. Conclusions: The ocular and internal spherical aberrations changed toward negative with mydriasis in the participants’ eyes suggesting the change of the ocular spherical aberration to be attributed to internal changes.

키워드

Aberrations, KR-1W, Mydriasis