50세 미만과 50세 이후에서 발생하는 안부 대상포진의 비교

• 영문명: Herpes Zoster Ophthalmicus in Patients Younger than 50 Years Versus 50 Years and Older
• 발행기관: 대한안과학회
• 저자명: 조가은 최규룡 전루민,Ga Eun Cho, MD, Kyu Ryong Choi, MD, PhD, Roo Min Jun, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume54,number1, 19~25쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2013.01.15

영문 초록

Purpose: To study the clinical course of herpes zoster ophthalmicus (HZO) and to compare the demographics, treatments, and outcomes in patients under 50 years of age versus patients 50 years of age or older at the time of diagnosis. Methods: A retrospective chart review was performed of 102 patients who were diagnosed with HZO between January 1, 2008 and December 31, 2010. Baseline demographics and clinical characteristics between patients with an onset of HZO under the age of 50 years and patients with an onset of HZO at the age of 50 years or older were compared. Results: Similar numbers of patients were affected with HZO in the younger and older age groups (n = 44, 43.1%, vs. n = 58, 56.9%). The mean ± SD of age was 50.6 ± 21.8 years (range, 3-89 years) and the most common decade of HZO onset was between 50 and 59 years. Gender and disease laterality were not statistically different between the 2 groups. No significant difference was found regarding the presence of any ocular manifestation between the groups; however, anterior uveitis was more frequent in the younger patients (p = 0.04). The number of patients with immunosuppressive therapy was higher in the younger age group (p = 0.01). Conclusions: HZO-affected patients under the age of 50 years and older than 50 years were equally distributed, with the most common decade of onset between the age of 50 and 59 years. Younger patients had a higher incidence of anterior uveitis and immunosuppressive therapy due to underlying systemic diseases.

키워드

Herpes zoster ophthalmicus, Immunity, Ocular complication, Young age