항생제 다제내성 아시네토박터 바우마니와 칸디다 파라프실로시스가 복합감염된 각막염 1예

• 영문명: A Case of Keratitis Caused by Combined Infection of Multidrug-Resistant Acinetobacter Baumannii and Candida Parapsilosis
• 발행기관: 대한안과학회
• 저자명: 최재광 김인혁 서정원,Jae Kwang Choi, MD, In Hyuk Kim, MD, Jeong Won Seo, MD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume53,number8, 1167~1171쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2012.08.15

영문 초록

Purpose: To report a case of keratitis caused by Acinetobacter baumannii and Candida parapsilosis in a patient using 0.5% levofloxacin and 0.1% fluorometholone for an extended period of time. Case summary: A 55-year-old male patient in the neurosurgery department with conjunctival injection and discharge in his left eye was consulted for ophthalmic evaluation and treatment. He was hospitalized in the state of akinetic mutism and given 0.5% levofloxacin and 0.1% fluorometholone for 2 years. On slit-lamp examination, a 3.5 × 4.5-mm dense stromal infiltrate with an overlying epithelial defect was observed. Corneal scraping culture revealed multidrug-resistant A. baumannii and C. parapsilosis. According to the susceptibility result, the patient was treated with topical 10% piperacillin/ tazobactam and 0.125% amphotericin B hourly. The corneal ulcer healed gradually with corneal opacity remaining after 8 weeks of treatment. Conclusions: The authors of the present study report a case of treated multidrug-resistant A. baumannii and C. parapsilosis keratitis in a patient using topical antibiotics and steroid for an extended period of time. J Korean Ophthalmol Soc 2012;53(8):1167-1171

키워드

Acinetobacter baumannii, Candida parapsilosis, Combined infection, Keratitis, Multidrug-resistant