녹내장 환자에서 안압의 하루 변동 반복성에 대한 고찰

• 영문명: Repeatability of Intraocular Pressure Patterns in Glaucomatous Patients
• 발행기관: 대한안과학회
• 저자명: 공민귀 이정민 기창원,Mingui Kong, MD, Jeong Min Lee, MD, Changwon Kee, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume53,number8, 1118~1123쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2012.08.15

영문 초록

Purpose: To investigate the repeatability of 24-hour intraocular pressure (IOP) patterns in glaucomatous patients. Methods: The author reviewed bilateral IOP data of 18 glaucoma patients who were admitted for 2 days. IOP data were collected in both eyes every 2 hours using Goldmann applanation tonometry during a 48-hour admission except at 02:00 o’clock (13 patients) and 04:00 o’clock (5 patients). The intraclass correlation coefficient was used to analyze the agreement of IOP patterns between the first and the second 24 hours. Results: IOP reached its peak between 04:00 o’clock and 06:00 o’clock in both eyes and on both days. On evaluation, the IOP data excluding the results of 02:00 o’clock and 04:00 o’clock, agreement of IOP values of 18 patients was good to excellent at 06:00, 18:00, 20:00, and 24:00 o’clock in both eyes. Agreement of IOP values at 08:00 and 12:00 o’clock was good in the right eye and the left eye, respectively. The agreement of IOP values of 13 patients who underwent IOP assessment at 04:00 o’clock and not at 02:00 o’clock, was good to excellent only at 04:00 and 06:00 o’clock in both eyes. Otherwise, agreement was poor or not significant except at 18:00 and 22:00 o’clock which showed good agreement in the right eye and the left eye, respectively. Conclusions: Presumable, a circadian IOP pattern exists, because in the present study, IOP reached its peak in the early morning on both days. However, to stipulate IOP patterns were repeatable appears to be difficult since there were numerous time points with poor agreement. J Korean Ophthalmol Soc 2012;53(8):1118-1123

키워드

Diurnal, Glaucoma, Intraocular pressure, Repeatability, Twenty-four-hour