레이저홍채절개술 단독 치료와 아르곤레이저주변홍채성형술 병용 치료 후 전안부빛간섭단층촬영 결과 비교

• 영문명: Change in Angle Parameters Measured by Anterior Segment Optical Coherence Tomography after Laser Peripheral Iridotomy Alone versus Laser Peripheral Iridotomy and Argon Laser Peripheral Iridoplasty
• 발행기관: 대한안과학회
• 저자명: 박형주 박기호 김석환 김태우 김동명,Hyung Ju Park, MD, Ki Ho Park, MD, PhD, Seok Hwan Kim, MD, PhD, Tae Woo Kim, MD, PhD, Dong Myoung Kim, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume52,number5, 566~573쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2011.05.15

영문 초록

Purpose: To compare the changes in angle parameters after laser peripheral iridotomy (LPI) alone versus LPI and ALPI (argon laser peripheral iridoplasty) in primary angle closure patients by using anterior segment optical coherence tomography (AS-OCT). Methods: A total of 25 eyes from 17 patients with narrow angles were enrolled in this present study. Eleven eyes in the LPI treatment group and 14 eyes in the LPI and ALPI combined treatment group were evaluated using AS-OCT. The anterior chamber depth (ACD), angle opening distance at 500 μm (AOD 500) and 750 μm (AOD 750), angle recess area at 500 μm (ARA 500) and 750 μm (ARA 750), trabecular-iris space area at 500 μm (TISA 500) and 750 μm (TISA 750), trabecular-iris angle (TIA) were measured. The pre- and post-treatment parameters were compared in each group. The parameter changes after laser treatment were also compared. Results: AOD 500, AOD 750, ARA 500, ARA 750, TISA 500 and TISA 750 except ACD significantly increased following LPI treatment (p = 0.013, p = 0.010, p = 0.008, p = 0.003, p = 0.006, p = 0.003, p = 0.013, respectively, Wilcoxon signed rank test) and LPI and ALPI combined therapy (p = 0.001, p = 0.001, p = 0.001, p = 0.001, p = 0.001, p = 0.001, p = 0.001, respectively, Wilcoxon signed rank test). The AOD 500 difference, TISA 500 difference, and TISA 750 difference were significantly greater after LPI and ALPI combined therapy than after LPI treatment alone (p = 0.112, p = 0.147, p = 0.049, p = 0.037, respectively, Mann-Whitney U-test). Conclusions: The results from the present study showed LPI alone or LPI and ALPI combined therapy significantly widened the anterior chamber angle and combined therapy showed greater effect than LPI alone. J Korean Ophthalmol Soc 2011;52(5):566-573

키워드

Anterior segment optical coherence tomography, Argon laser peripheral iridoplasty, Laser peripheral iridotomy