3회 이상 전층각막이식술을 시행 받은 환자의 장기간 임상결과와 이식실패의 위험인자

• 영문명: Long-Term Results after Three or More Penetrating Keratoplasties and Risk Factors for Graft Failure
• 발행기관: 대한안과학회
• 저자명: 장재용 우제문 윤경철,Jae Yong Jang, MD, Je Moon Woo, MD, Kyung Chul Yoon, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume52,number12, 1399~1404쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2011.12.15

영문 초록

Purpose: To evaluate the primary indications, surgical outcomes, causes and risk factors for graft failure in patients with three or more penetrating keratoplasty (PKP) surgeries. Methods: We retrospectively analyzed indications for the initial corneal graft, survival periods, causes and risk factors for failure in 25 patients (26 eyes) who had undergone three or more PKP with minimum follow-up periods of nine months. Results: The most common primary indications were herpes simplex keratitis (26.9%), followed by fungal keratitis (19.2%) and bacterial keratitis (11.5%). The average survival period of graft in three or more PKP was 12.9 ± 9.1 months. As the frequency of PKP increased, the survival period became shorter; the survival period was the longest in pseudophakic bullous keratopathy and the shortest in herpes simplex keratitis. The most common cause of graft failure was allograft rejection (82.8%), and the risk factors for graft failure were short interval between penetrating keratoplasties and corneal neovascularization. Conclusions: In three or more PKP, as the frequency of PKP increases, the survival period becomes shorter. Short interval between keratoplasties and cornel neovascularization were risk factors for graft failure; this results must be considered before surgery. J Korean Ophthalmol Soc 2011;52(12):1399-1404

키워드

Graft Failure, Risk Factor, Three or More Penetrating Keratoplasties