섬유주절제술 후 생체 분해성 콜라겐 기질의 섬유성 피막형성 1예

• 영문명: Fibrous Encapsulation of Biodegradable Collagen Matrix After Trabeculectomy: A Case Report
• 발행기관: 대한안과학회
• 저자명: 홍소진 이종락 김연덕 최진영 최재완,Sojin Hong, MD, Jong Rak Lee, MD, Yeon-Deok Kim, MD, Jin Young Choi, MD, Jaewan Choi, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume51,number4, 631~635쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2010.04.15

영문 초록

Purpose: Recently, biodegradable collagen matrix has been used as a possible substitute for anti-metabolite in trabeculectomy in order to control the responsiveness of the wound healing process. This paper reports a case of encapsulation of the biodegradable collagen matrix after trabeculectomy. Case summary: We conducted a fornix-based trabeculectomy on a 58-year-old man with medically uncontrollable steroid-induced glaucoma. We implanted biodegradable collagen matrix onto the sclera flap beneath the conjunctiva. Immediately after the surgery, we observed a localized bleb with high elevation. In the three months of follow-up, the bleb became encapsulated, and an increase in intraocular pressure was noted. During the wound revision, encapsulated material surrounded by thick fibrous membrane was found and removed from the subconjunctival space, followed by biopsy. Biopsy results demonstrated that amorphous collagenous material was surrounded by spindle and inflammatory cells. Conclusions: It is important to note that the fibrous encapsulation of collagen material is a possible complication of biodegradable collagen matrix-augmented trabeculectomy. J Korean Ophthalmol Soc 2010;51(4):631-635

키워드

Biodegradable collagen matrix, Complication, Ologen, Trabeculectomy