국내의 나이관련황반변성에 대한 기초역학조사

• 영문명: The Results of Nation-Wide Registry of Age-related Macular Degeneration in Korea
• 발행기관: 대한안과학회
• 저자명: 박규형 송수정 이원기 윤희성 고형준 김철구 김윤영 강세웅 김하경 이병로 남동흔 이필영 김형수 김형찬 김시열 정인영 김광수 허걸 오재령 김신동 이상준 김영덕 김순현 이태곤 조성원 이동초 장무환 김시동 조영욱 배선량 이주은 엄부섭 윤일한 권순일 강재훈 김종인 문상웅 유형곤 윤영희 장광열 이성철 이성진 박태관 온영훈 권오웅 장우혁 양연식 이석준 이수영외
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume51,number4, 516~523쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2010.04.15

영문 초록

Purpose: To evaluate the incidence and clinical features of age-related macular degeneration (AMD) in Korea Methods: Web-based (www.armd-nova.or.kr) registration was conducted for AMD patients aged 50 or more who were newly diagnosed by retinal specialists in Korea from August 20, 2005 to August 20, 2006. Patient data including ophthalmologic examination, fundus photography, fluorescein angiogram and/or indocyanin green angiogram (ICG), past medical history, behavioral habit, combined systemic diseases were up-loaded. Results: Among finally enrolled 1,141 newly diagnosed AMD patients, 690 patients (60.5%) were male and 451 patients (39.5%) were female. The average age of AMD patients was 69.7±8.0. Early AMD was observed in 190 patients and 951 patients had late AMD. Classic choroidal neovascular membrane (CNVM) was observed in 18.6% of exudative AMD patients and 63.4 % had occult CNVM. Subfoveal CNVM was observed in 80.4% of the patients with CNVM. Among the 580 exudative AMD eyes that performed indocyanin green angiography (ICG), 184 eyes (31.7%) had polypoidal choroidal vasculopathy (PCV) and 36 eyes (6.2%) showed retinal angiomatous proliferation (RAP). Age, male gender, smoking, diabetes and hypertension significantly increased the risk of the AMD among Koreans. Conclusions: Because of the low rate of participation by retinal specialists, definite incidence of AMD was not obtainable. However, the estimated 1-year AMD incidence in the Pusan area of Korea is at least 0.4%. In contrast to Western people, 31.7% of exudative AMD cases were revealed to be PCV and 6.2% were revealed to be RAP. This discrepancy between ethnic groups should be considered in the diagnosis and treatment modality selection of Korean AMD patients. J Korean Ophthalmol Soc 2010;51(4):516-523

키워드

Age-related macular degeneration, Choroidal neovascular membrane, Korean, Polypoidal choroidal vasculopathy