홍채고정 안내렌즈 삽입술 시행 후 각막내피세포의 장기 변화

• 영문명: Long-term Change in Corneal Endothelium After Iris-fixed Phakic Intraocular Lens Insertion
• 발행기관: 대한안과학회
• 저자명: 김성은 홍사민 이형근,Sung Eun Kim, MD, Sa Min Hong, MD, Hyung Keun Lee, MD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume50,number5, 677~683쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2009.05.15

영문 초록

Purpose: To investigate long-term endothelial changes in phakic eyes implanted with iris-claw phakic intraocular lens (IOL) (ArtisanⓇ lens Ophtec, Groningen, Netherlands) and to identify the associated factors. Methods: Thirty-one eyes of 18 patients underwent Artisan phakic IOL implantation and were followed up for over 1 year. The authors retrospectively examined the endothelial cell density, percentage of hexagonal cells and coefficient of variation using the result of non-contact specular microscope. Results: The mean endothelial cell loss was 0.9% at 23.9±9.44 months of the mean follow-up period. There was no statistically significant decrease in endothelial cell density (p=0.445). There was no statistically significant change in pleomorphism and polymegathism of the endothelial cells after the surgery. There was no statistically significant correlation between endothelial cell loss and anterior chamber depth (r2=0.0488, p=0.377). Conclusions: No clinically significant endothelial damage occurred after iris-claw phakic IOL implantation. However, special attention should be given to patients with shallow anterior chamber depth for iris-claw phakic IOL insertion to avoid unintended endothelial damage and long-term endothelial checkups using a specular microscope are critical for long-term protection of endothelial cells.

키워드

Corneal endothelial cell, Iris-claw phakic intraocular lens, Myopia