항바이러스제 정맥주사 및 유리체내 주입술을 병합하여 치료한 급성망막괴사 2예

• 영문명: Two Cases of Acute Retinal Necrosis Treated With Systemic Antiviral Drugs and Intravitreal Antiviral Injections
• 발행기관: 대한안과학회
• 저자명: 양지욱 김웅재 박영훈,Ji-Wook Yang, MD, Wung-Jae Kim, MD, Young-Hoon Park, MD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume50,number5, 794~799쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2009.05.15

영문 초록

Purpose: To report the use of intravitreal antiviral injections as adjunctive therapy in the managementof two immunocompetent patients with acute retinal necrosis. Case summary: We performed two or three intravitreal injections of gancyclovir (2,000 μg/0.05 ml) on two patients (two eyes) with acute retinal necrosis resistant to intravenous acyclovir therapy (1,500 mg/m2/day). Both patients received intravitreal antiviral injections for the treatment of retinitis that progressed despite standard intravenous acyclovir therapy. The retinitis resolved, and visual acuity improved after 18 months of follow-up in both cases. Conclusions: Intravitreal antiviral injections may be a safe and efficacious adjunctive therapy in the management of patients with acute retinal necrosis resistant to intravenous acyclovir therapy.

키워드

Acute retinal necrosis, Gancyclovir, Intravitreal injection