녹내장안에서 망막신경섬유층두께와 중심각막두께의 상관관계 분석

• 영문명: Relationship Between Central Corneal Thickness and Retinal Nerve Fiber Layer Thickness in Glaucomatous Subject
• 발행기관: 대한안과학회
• 저자명: 성경림 김동윤 남윤표,Kyung Rim Sung, MD, PhD, Dong Yoon Kim, MD, Yoon Pyo Nam, MD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume50,number3, 418~423쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2009.03.15

영문 초록

Purpose: To evaluate the correlation between central corneal thickness (CCT) and retinal nerve fiber layer thickness (RNFLT) as determined by optical coherence tomography (OCT) in glaucomatous subjects. Methods: One hundred eyes diagnosed with glaucoma and 99 glaucoma suspect (GS) eyes were tested by visual field (VF), OCT, and ultrasonic pachymetry. The relationship between CCT and RNFLT measurements was assessed by Pearson correlation analysis. A mixed effect model was employed to determine the relationship between CCT and RNFLT in glaucoma and GS groups. We divided the patients into two groups depending on the thickness of their corneas: Thin (< 553.6 μm) and thick (≥ 553.6 μm), and compared three parameters: VF mean deviation (MD), pattern standard deviation (PSD), and RNFLT between the two groups. Results: There were no significant correlations between CCT and RNFLT in any participant (R2=0.00, p=0.88). There was no significant relationship between CCT and RNFLT in glaucoma and GS groups (p=0.11, p=0.46). There were no statistically significant differences in MD, PSD, or RNFLT between the thin and thick cornea groups (p=0.38, 0.32, 0.44). Conclusions: CCT is not significantly associated with RNFLT in glaucoma and GS subjects.

키워드

Central corneal thickness, Optical coherence tomography, Retinal nerve fiber layer thickness