쥐에서 리바운드 안압계와 토노펜의 안압측정치 비교

• 영문명: Comparison of the Intraocular Pressure Measurement between Rebound Tonometer and Tonopen in Rats
• 발행기관: 대한안과학회
• 저자명: 유영철 김석환 김유정 박기호,Young Cheol Yu, M.D.,, Seok Hwan Kim, M.D.,, Yu Jeong Kim, Ki Ho Park, M.D.,
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume48,number1, 135~141쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2007.01.31

영문 초록

Purpose: To compare the rebound tonometer with the TonoPen for measuring the intraocular pressure (IOP) in rats Methods: Chronic IOP elevation models were induced unilaterally in nine Sprague-Dawley rats by applying an argon laser to the trabecular meshwork. IOP was measured before laser treatment and at one, two, and three days following laser treatment. Two independent operators collected five readings of the rebound tonometer and the TonoPen. Correlation analysis and comparison with the Bland & Altman method were performed. The intraclass correlation coefficient of each measurement and the difference between two independent operators were calculated. Results: The IOP values measured with the rebound tonometer were well correlated with those of the TonoPen (r=0.676, p<0.001); however, the mean difference expressed as the percent difference of the averages of two tonometers, was 27.5%. The IOP values measured with a rebound tonometer exhibited a significantly higher intraclass correlation coefficient (0.966; 95% CI, 0.945-0.980 vs 0.412; 95% CI, 0.264-0.581) and a lower difference between the two operators (3.10±2.17 mmHg vs 6.17±5.17 mmHg) than those of the TonoPen. Conclusions: Although the IOP values measured with the rebound tonometer were lower than those of the TonoPen, they were in good agreement and were less variable than those of the TonoPen.

키워드

IOP measurement, Rat, Rebound tonometer, Tonopen