다양한 각막표면질환에서 양막이식술의 임상적 효과

• 영문명: The Clinical Effect of Amniotic Membrane Transplantation for Various Ocular Surface Diseases
• 발행기관: 대한안과학회
• 저자명: 이기환 이동욱 김인철,Ki Hwan Lee, M.D., Dong Wook Lee, M.D., In Cheol Kim, M.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume48,number1, 7~12쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2007.01.31

영문 초록

Purpose: To describe the clinical outcome of amniotic membrane transplantation(AMT) for various ocular surface diseases. Methods: We reviewed the medical records of 52 eyes from 46 patients which had underwent AMT for various ocular surface diseases. We scored each eyes from 0 to 4 for subjective symptoms (symptom score) and epithelial healing (epithelial grade) at three months after AMT. The clinical score was calculated as the symptom score time the epithelial grade. Results: The mean clinical score among all ocular surface disease was 10.41±4.26. The mean clinical scores for each disease are as follows: 7.71±3.56 for corneal ulcers, 14.43±3.1 for persistent epithelial defects, 12.83±2.71 for exposure keratitis, 12.86±3.18 for herpes keratitis, 5.85±2.5 for bullous keratopathy, 10.53±4.27 for chemical corneal burns and 16.0±0.0 for shield ulcers. Subjective symptoms subsides and epithelial healing progressed in all patients treated by AMT. No complications occurred. Conclusions: AMT is an effective method for treating various ocular surface diseases, because AMT improves the subjective symptoms of patients and promotes the healing of epithelial lesions.

키워드

AMT (Amniotic membrane transplantation), Clinical score, Ocular surface disease