다공성 폴리에틸렌 안와 삽입물의 피복 재료로서 신전된 폴리테트라플루오로에틸렌의 이용

• 영문명: Expanded Polytetrafluoroethylene as a Wrapping Material for Porous Polyethylene Orbital Implant
• 발행기관: 대한안과학회
• 저자명: 김상진 곽상인 정호경-,Sang Jin Kim, M.D.,, Sang In Khwarg, M.D., Ph.D.,, Ho Kyung Choung, M.D., Ph.D,,
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume48,number1, 117~124쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2007.01.31

영문 초록

Purpose: To investigate the possibility of expanded polytetrafluoroethylene (e-PTFE) as a wrapping material for porous polyethylene orbital implant. Methods: Two groups of 6 female New Zealand albino rabbits underwent enucleation with placement of a 12 mm porous polyethylene orbital implant wrapped in simple e-PTFE in one group (group 1) and macro-porous e-PTFE in the other group (group 2). Histopathologic sections of the implants obtained at 4, 6, 8 weeks were compared on the extent of fibrovascular ingrowth, percentage of the area of proliferated vessel, and grade of fibrosis between the two groups. Results: There was no implant exposure or severe inflammation in group 1 and 2 during the observation. The extent of fibrovascular ingrowth differs only at 4 weeks. Group 1 showed less fibrovascular ingrowth (until outer 1/3) at anterior half compared with posterior one, but there was no difference between anterior and posterior half in group 2 (until middle 1/3). The percentage of the area of the proliferated vessels was higher in group 2 than group 1 at both anterior and posterior half, and the anterior/posterior ratio of the area of vessels was also higher in group 2 than group 1. The grade of fibrosis was higher in group 2 than group 1 at 4, 6, and 8 weeks. Conclusions: Macro-porous e-PTFE almost didn`t disturb fibrovascular ingrowth into the orbital implant, so macro-porous e-PTFE can be used safely as a wrapping material for porous polyethylene orbital implant.

키워드

Expanded Polyetetrafluoroethylene, Porous polyethylene orbital implant, Wrapping material